GNC Men’s Yohimbe 451, Pure Extract, 60 Capsules

8 reviews for GNC Men’s Yohimbe 451, Pure Extract, 60 Capsules

1. 

   Rated 5 out of 5

   Merc – May 29, 2026

   This stuff really puts some lead in your pencil. Consult your physician before using this if you have any heart conditions and be careful when you first start taking it because it can cause some anxiety/discomfort at full dose. Once you get used to it its pretty managable.

   This is a really interesting supplement. It is a norepinephrine inhibitor which means it artificially increases the concentration of norepinephrine in your brain and body. This results in a lot of interesting physical and mental effects. Physically this can help a lot with workouts and training, I feel invigorated and responsive when I’m training on this supplement. Mentally this supplement can affect your mood in various ways; I typically feel a touch euphoric and outgoing when I am supplementing with this and maybe on the negative side I can feel a bit wound up/edgy. Finally this stuff definitely increases libido, enough said there.

   This is an interesting supplement in the context of training at the gym and perhaps could be helpful for mood augmentation as well as giving you a little more pep with your significant other.

2. 

   Rated 5 out of 5

   Amazon Customer – June 16, 2026

   All the crazy side effects reviewed here are the reasons why experienced yohimbe users take this. I have been using GNC 451 for years and i still will not dare more than 1 capsule at my weight of 180 pounds. 1/3 to 2/3 capsule on empty stomach will have desired effect. The “nervous” energy that ensues from yohimbe can be channeled into incredible sexual energy. If you take a few capsule it will bring you to hell. Respect this product because I am very grateful it has not been banned in US. I have tried other brands of yohimbe/yohimbine with almost placebo effects. The GNC 451 is the confirmed effective genuine yohimbie. And do your research on drug interactions because this can cause very dangerous situations if mixed with the wrong drug.

3. 

   Rated 5 out of 5

   J Raden – June 21, 2026

   This GNC Yohimbe is awesome. Just 1 of these in the morning gets you going.

   I am usually tired all day but this helps with that a bit. It makes you sweat much more easily; I’d get sweaty armpits after my walk to work (in mild/cool temperature) that I normally don’t get. It gave me a slightly reduced appetite. It certainly made me feel more invincible in the gym; I had more energy to push myself on a tough elliptical interval workout.

   …and yup, it gives ya extra strong boners.

   What everyone says about the jitteriness is true though. If you have trouble sleeping I would never take this any time after first thing in the morning, cause it jazzes you up. It does make you a little nervous too, and from the reviews it’s clear this affects some people more than others. For me it was not a huge deal at all and the extra energy was easily worth a little sweating and jitters (no worse than I get after a couple coffees or a Sudafed).

   LOVE these and will buy again.

4. 

   Rated 5 out of 5

   Zeimus – July 1, 2026

   This stuff works. You just have to know what you’re doing. I was taking two pills a day and felt the effect of a slightly raised metabolism (start with one in the morning, then take one later, and once you adjust you can take two at once). Below I will provide an excerpt from Examine with some facts:

   Dosages of 0.2mg/kg bodyweight have been successfully used to increase fat burning without significant implications on cardiovascular parameters like heart rate and blood pressure. This results in a dosage of:

   14 mg for a 150lb person

   18 mg for a 200lb person

   22 mg for a 250lb person

   Supplementation is most effective between meals or during short term fasting.

   Caution should be exercised at higher body weight, since the cardiovascular system may not be prepared to handle a stimulatory agent such as yohimbine. When supplementing yohimbine for the first time, always start with a half-dose and assess tolerance before proceeding.

   When pairing yohimbine with other stimulatory agents, half-dose both supplements and work up to the recommended dose cautiously, as two supplements can interact negatively.

5. 

   Rated 1 out of 5

   Lincoln Don Washington – July 15, 2026

   Those types of nutrients most of the times are good or work perfectly for some people but a disaster for others. the first one I took, I waited about an hour and a half before I started, nothing works, I had a soft penis and lasted less than two minutes. This was not the problem because truthfully those things never work on me. The problem is Sialorrhea meaning Excessive Saliva Production?

   All medications come paired with some sort of side effects. Excessive saliva production may be one of them. If you think this may be the cause of your mouth watering, do not stop any medications before talking with your doctor.

   Know the Signs

   Besides the more obvious signs of hypersalivation such as drooling or spitting, other symptoms may include:

   Bad breath

   Chapped lips

   Dehydration

   Difficulty eating or drinking

   Changes in speech

   Even though mouth watering may be annoying, there’s a good chance it’s not caused by something incredibly serious. However, that doesn’t mean you should ignore it. The best thing you can do is see a dentist to better understand the root cause as well as the best treatment option for you.

   I spent the night spitting I could not sleep.

6. 

   Rated 4 out of 5

   Steve H – July 16, 2026

   I purchased this for the reasons most guys do, sexual health and energy. I’m 68 and very fit with no health problems. I read all the reviews with comments about their hearts racing, blood pressure, elevating, going to ER, etc. So I decided to start slow and see how I did with this product. First 10 days I opened one capsule and divided into 3 smaller doses and put supp into empty gelatin capsules. I tried it early morning on an empty stomach; not so great. I tried it with a meal and that worked better. I decided to only take this on days I’m training. I’m now up to 1/2 capsule. I take it about 1 hours before training. I not drinking an energy drink at the same time I take yohimbe. No problems so far. I’m accustomed to energy drinks etc one per day before my workout. Energy from this feels different than an energy drink. The best description is how I felt 20 years ago taking ephedrine prior to the gym. After a set I find myself up moving or pacing before the next set. I’m warm but not really sweaty. When I’m finished with my training I feel like I could easily stay at the gym another hour. The effects seem to last about 5-6 hours, so I never take it any later later than 2:30 or 3:00. I like my 8 hours of sleep each night. Sexual benefits? Too early to tell, but I already take 10 mg Tadalafil every other day and 300-400 mg of LJ100 tongkat daily. So my recommendation is to start low on dosing and take a month to work up to larger amounts or a full capsule (which I haven’t tried yet). And don’t take it on days you are sitting around the house all day working on your computer; you need to be active to expend the physical energy it produces. Maybe I’ll update again in about 30 days.

7. 

   Rated 3 out of 5

   Glenn – July 27, 2026

   Having taken this product before (Yohimbe) it is not as potent as in the past. I’m not sure because I purchased this through Amazon and not at a store. With an additional pill (3) it starts to kick in.

8. 

   Rated 5 out of 5

   Black Diamond Social Club – July 31, 2026

   i find this to be the best yohimbe out there. the twin lab version is pretty good but gives inconsistent results. The GNC version is a little more expensive but find it most consistent in delivery/time to kick in and results. worth the extra price. been buying this one for about ten years, trying out other brands here and there, but always come back to this exact product.